2025

Walunj, S., Mishra, G., Wagstaff, K. M., Patankar, S. and Jans, D. A. The ivermectin related compound moxidectin can target apicomplexan importin α and limit growth of malarial parasites. (2025). Cells. 14(1), 39. 

2024

Bhambid, M., Walunj, S., Anupama, C. A., Jain, S., Mehta, D., Wagstaff, K. M., Panda, A., Jans, D. A., Mohmmed, A. and Patankar, S. (2024). Importin α inhibitors act against the differentiated stages of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii. Journal of Antimicrobial Chemotherapy, 2024. Preprint available at bioRxiv, doi: https://doi.org/10.1101/2024.07.10.602875 

Anjum, S., Prasad, A., Mastud, P., Mishra, G. and Patankar, S. (2024). N-terminal targeting sequences and coding sequences act in concert to determine the localization and trafficking pathway of apicoplast proteins in Toxoplasma gondii. Biology of the Cell. 116(12):e2400027.

Ilamathy P., Walunj, S., Banerjee, N., Rout, J., Srivastava, S., Patankar, S.* and Kaledhonkar, S*. (2024). Application of Bio-Layer Interferometry for the Analysis of Ribosome-Protein Interactions. Frontiers in Molecular Biosciences. 11, 1398964.

* Corresponding authors

Mishra, V., Deshmukh, A., Rathore, I., Chakraborty, S., Patankar, S., Gustchina, A., Wlodawer, A., Yada, R. Y. and Bhaumik, P. (2024). Inhibition of Plasmodium falciparum plasmepsins by drugs targeting HIV-1 protease: a way forward for antimalarial drug discovery. Current Research in Structural Biology. 7, 100128.

2023

Anjum, S., Prasad, A., Mastud, P. and Patankar, S. (2023). N-terminal targeting sequences and coding sequences act in concert to determine the localization and trafficking pathway of apicoplast proteins in Toxoplasma gondii. Preprint available at bioRxiv, doi: https://doi.org/10.1101/2023.06.20.545694. 

Bhambid, M., Dey, V., Walunj, S. and Patankar, S. (2023). Toxoplasma gondii importin alpha shows weak auto-inhibition. Protein Journal. 42(4):327-342. Preprint available at bioRxiv, doi: https://doi.org/10.1101/2022.10.06.510747 

Aggarwal, S., Selvaraj, S., Jayaprakash N. S., Vijayalakshmi M. A., Patankar, S., and Srivastava, S. (2023). Polyclonal antibody generation against PvTRAg for the development of a diagnostic assay for Plasmodium vivax. Diagnostics. 13(5), 835. 

2022

Walunj, S., Wang, C., Wagstaff, K., Patankar, S. and Jans, D. A. (2022). Conservation of the classical nuclear import machinery in apicomplexans: ivermectin and GW5074 as potential therapeutics for malaria and toxoplasmosis. International Journal of Molecular Sciences. 23(22), 13899. 

Chakrabarti, R., Chery-Karschney, L., White, J., Mascarenhas, A., Skillman, K. M., Kanjee, U., Babar, P. H., Patrapuvich, R., Mohapatra, P. K., Patankar, S., Smith, J. D., Anvikar, A., Valecha, N., Rahi, M., Duraisingh, M. T. and Rathod, P. K. (2022). Diverse malaria presentation across NIH South Asia ICEMR sites in India. American Journal of Tropical Medicine & Hygiene. 107(4_Suppl),  107-117.

Walunj, S.B., Dias, M. M., Kaur, C., Wagstaff, K. M., Dey, V., Hick, C., Patankar, S.* and Jans, D. A.* (2022). High-throughput screening to identify inhibitors of Plasmodium falciparum importin a. Cells. 11(7), 1201.

* Equal contribution.

2021

Mishra, V., Rathore, I., Deshmukh, A., Patankar, S., Gustchina, A., Wlodawer, A., Yada, R. Y. and Bhaumik, P. (2021). Molecular insights into the inhibition of plasmepsins by HIV-1 protease inhibitors: Implications for antimalarial drug discovery. Preprint available at bioRxiv, doi: https://doi.org/10.1101/2021.09.27.461917.

Prasad, A. and Patankar, S. (2021). Recognition of two distinct pathways for trafficking of proteins to the apicoplast. Letter to the editor. mBio. 12 (6).

Venkatesh, A., Jain, A., Davies, H., Rathod, P. K., Patankar S. and Srivastava S. (2021). Protein Arrays for the Identification of Seroreactive Protein Markers for Infectious Diseases. Methods in Molecular Biology. 2344,139-150.

Kaur, C. and Patankar, S. (2021). The role of upstream open reading frames in translation regulation in the Apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii. Parasitology. 148(11), 1277-1287. Preprint available at Preprints doi: 10.20944/preprints202104.0680.v1.

Prasad, A., Mastud, P. and Patankar, S. (2021). Dually localized proteins found in both the apicoplast and mitochondrion utilize the Golgi-dependent pathway for apicoplast targeting in Toxoplasma gondii. Biology of the Cell. 113 (1), 58-78. Preprint available at bioRxiv doi:10.1101/2020.03.25.007476. 

2020

Kumar, V., Ray, S., Aggarwal, S., Biswas, D., Jadhav, M., Rao, R., Sabnis, S. V., Banerjee, S., Talukdar, A., Kochar, S., Shetty, S., Sehgal, K., Patankar S. and Srivastava, S. (2020). Multiplexed Quantitative Proteomics Provides Mechanistic Cues for Malaria Severity and Complexity. Communications Biology. 3(1):683.

Kaur, C., Kumar, M. and Patankar, S. (2020). Messenger RNAs with large numbers of upstream open reading frames are translated via leaky scanning and reinitiation in the asexual stages of Plasmodium falciparum. Parasitology. 147 (10), 1100-1113. Preprint available at bioRxiv doi: https://doi.org/10.1101/823443.

*Chosen as the “article of the month” by Parasitology journal and the first author was interviewed by Biopatrika science magazine.

Venkatesh, A., Aggarwal, S., Kumar, S., Rajyaguru, S., Kumar, V., Bankar, S., Shastri, J., Patankar, S., and Srivastava, S. (2020). Comprehensive proteomics investigation of P. vivax-infected human plasma and parasite isolates. BMC Infectious Diseases. 20 (1), 1-11.

2019

Pany, S. P. P., Sapra, M., Sharma, J., Dhamodharan, V., Patankar, S. and Pradeepkumar, P. I. (2019). Presence of potential G-quadruplex RNA forming motifs at the 5’-UTR of PP2Acα mRNA inhibit translation. ChemBioChem.  20(23):2955-2960.

Mastud, P. and Patankar, S. (2019). An ambiguous N-terminus drives the dual targeting of an anti-oxidant protein, TgTPx1/2, to endosymbiotic organelles in the apicomplexan Toxoplasma gondii. PeerJ. 7:e7215. Preprint available at bioRxiv, doi: https://doi.org/10.1101/562587. 

Venkatesh, A., Jain, A., Davies, H., Pereira, L., Maki, J. N., Gomes, E., Felgner, P. L., Srivastava, S., Patankar, S. and Rathod, P. K. (2019). Hospital-derived antibody profiles of malaria patients in SW India. Malaria Journal. 18(1):138-152.

2018

Narayan A., Mastud, P., Thakur, V., Rathod, P. K., Mohmmed A. and Patankar, S. (2018). Heterologous expression in Toxoplasma gondii reveals a topogenic signal anchor in a Plasmodium apicoplast protein. FEBS Open Bio. 8: 1746-1762. 

* Cover page image from this paper.

Dey, V. and Patankar, S. (2018). Molecular basis for the lack of auto-inhibition of P. falciparum importin alpha. Biochemical and Biophysical Research Communications. 503(3):1792-1797. 

Mishra, V., Rathore, I., Arekar, A., Xiao, H., Patankar, S., Gustchina, A., Hidaka, K., Wlodawer, A., Yada, R., Bhaumik, P. (2018). Molecular insights into nanomolar inhibition of P. falciparum plasmepsins: Implications for structure-based antimalarial drug discovery. FEBS Journal. 285: 3077-3096.

Patankar, S., Sharma, S., Rathod, P. K. and Duraisingh, M. (2018). Malaria in India: The need for new targets for diagnosis and detection of Plasmodium vivax. Invited review article, Proteomics: Clinical Applications. 12(4): e1700024.

2017

Awasthi, G., Tyagi, S., Kumar, V., Patel, S. K., Rojh, D., Sakrappanavar, V., Kochar, S. K., Talukdar, A., Das, A., Srivastava, S. and Patankar, S. (2018). A proteo-genomic analysis of haptoglobin and malaria. Proteomics: Clinical Applications. Jul;12(4): e1700077.

Venkatesh, A., Lahiri, A., Reddy, P. J., Shastri, J., Patankar, S. and Srivastava, S. (2018). Identification of highly expressed Plasmodium vivax proteins from clinical isolates using proteomics. Proteomics: Clinical Applications. Jul;12(4): e1700046.

* Cover page image from this paper.

Ray, S., Patel, S. K., Venkatesh, A., Chatterjee, G., Ansari, N. N., Gogtay, N., Thatte, U., Patankar S. and Srivastava, S. (2017). Proteomic Analysis of Extremely Low and Moderate Parasitemic and Longitudinal Cohorts of Vivax Malaria Patients for Identification of Potential Disease Monitoring Serum Biomarkers. Scientific Reports, 7(1):4400.

Chaudhari, R.*, Sharma, S. and Patankar, S. (2017). Glutathione and thioredoxin systems of the malaria parasite Plasmodium falciparum: Partners in crime? Biochemical and Biophysical Research Communications, 488(1):95-100. Preprint available at bioRxiv, doi: https://doi.org/10.1101/128264.

* Corresponding author.

Chaudhari, R., Narayan, A., Dey, V., Sharma, S. and Patankar, S. (2017). Membrane and luminal proteins reach the apicoplast by different trafficking pathways in the malaria parasite Plasmodium falciparum. PeerJ, 5:e3128.

2016

Babar, P. H., Dey, V., Jaiswar, P. and Patankar S. (2016). An insertion in the methyltransferase domain of P. falciparum trimethylguanosine synthase harbors a classical nuclear localization signal. Molecular Biochemical Parasitology, 210(1-2): 58-70.

Chakrabarti, R. and Patankar, S. (2016). Combination assays and molecular docking can identify binding sites of anti-microtubule drugs on Plasmodium falciparum tubulin. Infectious Disorders-Drug Targets, 16(3): 204-216.

Venkatesh, A., Patel, S. K., Ray, S., Shastri, J., Chatterjee, G., Kochar, S. K., Patankar S. & Srivastava S. (2016). Proteomics of Plasmodium vivax malaria: New insights, progress and potential. Expert Review of Proteomics, 13(8): 771-82.

Ray, S., Patel, S. K., Bhave, A., Venkatesh, A., Kumar, V., Singh, V., Chatterjee, G., Shah, V.G., Sharma, S., Durairaj R., Ansari, N. N., Gandhe, P., Gogtay, N., Thatte, U., Sehgal, K., Verma, S., Karak, A., Khanra, D., Talukdar, A., Kochar, S., Kochar, D., Rojh, D., Gandhi, M., Varma, S.G., Srikanth, R., Patankar, S. and Srivastava, S. (2016). Clinicopathological Analysis and Multipronged Quantitative Proteomics Reveal Oxidative Stress and Cytoskeletal Proteins as Possible Markers for Severe Vivax Malaria. Scientific Reports 6: 24557.

Srinivas, V., Kumar, M., Noronha, S. and Patankar, S. (2016). ORFpred: A machine learning program to identify translatable small open reading frames in intergenic regions of the Plasmodium falciparum genome. Current Bioinformatics 11(2): 259-268. 

2015

Kumar, M., Srinivas, V. and Patankar S. (2015). Upstream AUGs and upstream ORFs can regulate the downstream ORF in Plasmodium falciparum. Malaria Journal 14: 512.

Ray, S., Kumar, V., Bhave, A., Singh, V., Gogtay, N., Thatte, U., Talukdar, A., Kochar, S. K., Patankar, S., Srivastava, S. (2015). Proteomic Analysis of Plasmodium falciparum Induced Alterations in Humans from Different Endemic Regions of India to Decipher Malaria Pathogenesis and Identify Surrogate Markers of Severity. Journal of Proteomics 127(Pt A): 103-13.

2014

Patankar, S., Narayan, A., Chaudhari, R. and Chakrabarti, R. (2014). Translation initiation and termination in the human malaria parasite Plasmodium falciparum. Encyclopedia of Malaria. Published by Springer, edited by Marcel Hommel and Peter G. Kremsner, 10.1007/978-1-4614-8757-9_55-1.

2013

Walawalkar, Y. D., Phadke, R., Noronha, S., Patankar, S. and Pillai, B. (2013). Engineering whole-cell biosensors to evaluate the effect of osmotic conditions on bacteria. Annals of Microbiology 63(4): 1283-1290.

Chakrabarti, R., Rawat, P. S., Coppel, R., Cooke, B. M. and Patankar, S. (2013). Cellular effects of curcumin on Plasmodium falciparum include disruption of microtubules. PLoS ONE 8(3).

2012

Chaudhari, R., Narayan, A. and Patankar, S. (2012). A novel trafficking pathway in P. falciparum for the organellar localization of glutathione peroxidase-like thioredoxin peroxidase. FEBS Journal. 279(20): 3872-3888.

Narayan, A., Kumar, M., Singh, M., Babar, P., Chaudhari, R. and Patankar, S. (2012). Regulation of gene expression in P. falciparum. Current Science 102(5): 712-724.

Patakottu, B.R., Singh, P. K., Malhotra, P., Chauhan, V. S. and Patankar, S. (2012). In vivo analysis of translation initiation sites of P. falciparum. Molecular Biology Reports 39(3): 2225-32.

Ray, S., Renu, D., Srivastava, R., Gollapalli, K., Taur, S., Jhaveri, T., Dhali, S., Chennareddy, S., Potla, A., Bajpai Dikshit, J., Srikanth, R., Gogtay, N., Thatte, U., Patankar, S. and Srivastava, S. (2012). Proteomic investigation of falciparum and vivax malaria for identification of surrogate protein markers. PLoS ONE 7(8).

Ray, S., Srivastava, R., Tripathi, K., Vaibhav, V., Patankar S. and Srivastava S. (2012). Serum Proteome Changes in Dengue Virus-Infected Patients from a Dengue-Endemic Area of India: Towards New Molecular Targets? OMICS 16(10): 527-36.

Ray, S., Kamath, K. S., Srivastava, R., Raghu, D., Gollapalli, K., Jain, R., Gupta, S. V., Ray, S., Taur, S., Dhali, S., Gogtay, N., Thatte, U., Srikanth, R., Patankar, S. and Srivastava, S. (2012). Serum Proteome Analysis of Vivax Malaria: Mechanistic Insight into the Disease Pathogenesis and Host Immune Response. Journal of Proteomics 75(10): 3063-80.

Aditya, N.P., Chimote G., Gunalan K., Banerjee R., Patankar, S. and Madhusudhan B. (2012). Enhanced antimalarial activity and protective effect of curcuminoids-loaded liposomes against Plasmodium berghei infection in mice. Experimental Parasitology 131(3): 292-9.

Gore, K. R., Nawale, G. N., Harikrishna, S., Chittoor, V. G., Pandey, S., Höbartner, C., Patankar, S. and Pradeepkumar P. I. (2012). Synthesis, Gene Silencing and Molecular Modelling Studies of 4’-C-Aminomethyl-2’-O-Methyl Modified Small Interfering RNAs. Journal of Organic Chemistry 77(7): 3233–3245.

2011

Kathpal, A., Patakottu, B.R. and Patankar, S. (2011). FORS-D analysis in P. falciparum can differentiate classes of genes under selection. Evolutionary Bioinformatics 7: 21-29.

Panneerselvam, P., Bawankar, P., Kulkarni, S. and Patankar, S. (2011). Computational identification of evolutionarily conserved GC-rich elements associated with immunogenic proteins of Plasmodium falciparum. Evolutionary Bioinformatics 7: 235-55.

2010

Bawankar, P., Shaw, P.J., Sardana, R., Babar P.H. and Patankar, S. (2010). 5′ and 3′ end modifications of spliceosomal RNAs in P. falciparum. Molecular Biology Reports 37(4): 2125-2133.

Aditya, N.P., Patankar, S. and Madhusudan, B. (2010). Assessment of in vivo antimalarial activity of rifampicin, isoniazide and ethambutol combination therapy. Parasitology Research 106(6): 1481-4.

Aditya, N.P., Patankar S., Madhusudhan, B., Murthy, R.S.R. and Souto, E.B. (2010). Artemeter-loaded lipid nanoparticles produced by modified-thin film hydration: pharmacokinetics, toxicological and in vivo anti-malarial activity. European Journal of Pharmaceutical Sciences 40(5): 448-55.

Aditya, N.P., Tiyaboonchai W., Patankar, S., Madhusudhan, B. and Souto, E.B. (2010). Curcuminoids-loaded lipid nanoparticles: Novel approach towards malaria treatment. Colloids and Surfaces B: Biointerfaces 81(1): 263-273.

2009

Aditya, N.P., Patankar, S. and Madhusudhan, B. (2009). Assessment of combined anti-malarial activity of α, β arteether and primaquine against Plasmodium berghei in vivo. Pharmacologyonline 1: 588-596.

Patakottu, B.R., Mamidipally, C., Patankar, S.* and Noronha, S. (2009). In silico analysis of translation initiation sites from P. falciparum. Online Journal of Bioinformatics 10(2): 259-279. 

* Corresponding author.

Aditya, N.P., Patankar, S. and Madhusudhan, B. (2009). Assessment of curcumin-primaquine combination therapy for malaria. Pharmacologyonline 3: 49-53.

2005

Upadhyay, R., Bawankar, P., Malhotra D. and Patankar S. (2005). A screen for conserved sequences with biased base composition identifies noncoding RNAs in the A-T rich genome of Plasmodium falciparum. Molecular and Biochemical Parasitology 144(2): 149-58.

Publications from Swati's postdoctoral research

2004

Munasinghe-Gunasekera, A., Patankar, S., Eisen, G., Schug, J., Kissinger, J., Roos, D. & Wirth, D.F. (2004). Widespread distribution of antisense transcripts in the Plasmodium falciparum genome. Molecular and Biochemical Parasitology 136(1): 35-42.

2003

Myrick, A., Munasinghe, A., Patankar, S., & Wirth, D.F. (2003). Mapping of the Plasmodium falciparum multi-drug resistance gene 5′ upstream region and evidence of transcript induction by antimalarial drugs in chloroquine sensitive parasites. Molecular Microbiology 49(3): 671-683.

Munasinghe-Gunasekera, A., Patankar, S., Schug, J., Eisen, G. & Wirth, D.F. (2003). Drug-induced alterations in gene expression of the asexual blood forms of Plasmodium falciparum. Molecular Microbiology 50(4): 1229-1239.

2001

Munasinghe A.*, Patankar, S.*, Cook, B.P., Madden, S.L., Martin, R.K., Kyle, D.E., Shoaibi, A., Cummings, L.M. & Wirth D.F. (2001). Serial Analysis of Gene Expression (SAGE) in Plasmodium falciparum: application of the technique to A-T rich genomes. Molecular and Biochemical Parasitology 113(1): 23-34.   

* These authors made equal contributions to the work.

Patankar, S.*, Munasinghe, A.*, Shoaibi, A., Cummings, L.M. & Wirth D.F. (2001). Serial Analysis of Gene Expression in Plasmodium falciparum reveals the global expression profile of erythrocytic stages and the presence of anti-sense transcripts in the malarial parasite. Molecular Biology of the Cell 12 (10): 3114-3125.

* These authors made equal contributions to the work.

2000

Patankar, S., Fujioka, H. & Wirth D.F. (2000). The signal sequence and C-terminal hydrophobic domain are required for localization of the sexual stage antigen Pgs28 to the surface of P. gallinaceum ookinetes. Molecular and Biochemical Parasitology 111(2): 425-435.